Oncologist reveals difficult side effects of chemotherapy include tiredness, nausea and hair loss – as Princess of Wales undergoes ‘preventative’ cancer treatment

A top oncologist has revealed the possible side effects the Princess of Wales could face if she undergoes ‘preventative’ cancer chemotherapy.

Princess Catherine may experience fatigue, nausea and vomiting while being treated for the disease, says Dr. Matt Williams.

The future queen, who could also have problems with her body producing enough red and white blood cells, increasing the risk of infection.

Dr. Williams, a consultant at The London Clinic, where Kate underwent major abdominal surgery in January, said she could experience some hair loss depending on the medications she is taking.

It comes days after the mother-of-three shocked the nation by revealing she was diagnosed with cancer after surgery and is being given medication to prevent the disease from returning.

The Princess of Wales pictured at the opening of a day surgery unit in London on December 5, 2023

Oncologist Dr Matt Williams told ITV News that Kate can expect side effects from her treatment, including fatigue, nausea and possible hair loss.

Oncologist Dr Matt Williams told ITV News that Kate can expect side effects from her treatment, including fatigue, nausea and possible hair loss.

The world has rallied behind the Princess of Wales since she announced the news in a televised address on Friday evening, with thousands sending well wishes.

What is preventive chemotherapy?

Chemotherapy is a form of cancer treatment that uses powerful drugs to tackle the disease but causes many side effects on the body, including hair loss.

It can be used to treat cancer directly, shrink a tumor in preparation for surgery, or prevent cancer from returning.

When used to prevent the disease from recurring, it may also be called adjuvant chemotherapy.

It is usually given as an infusion or tablets, and depending on the type of medicine, these can be taken at home or in hospital.

The purpose of this is to prevent small cancer cells from taking root in the body.

This works because the drugs are cytotoxic, meaning they are toxic to cells and especially to cells that are dividing rapidly.

Because cancer cells divide more than healthy cells, they are more affected by chemotherapy, which is why it is used as a treatment for the disease.

However, other types of fast-growing cells, such as hair, bone marrow, skin and the lining of the digestive system, are also damaged.

The 42-year-old revealed doctors had discovered an unspecified form of cancer and she is undergoing ‘preventive’ chemotherapy.

Dr. Williams told ITV News that the medications Kate is taking will have some impact on her quality of life.

‘The side effects of chemotherapy depend somewhat on the medicines you take, but generally include fatigue, nausea, perhaps vomiting, blood count problems and the risk of infection,’ he said.

“Some people will lose their hair, but that largely depends on exactly what medications you’re taking.”

Professor Pat Price, an academic clinical oncologist at Imperial College, said these types of side effects are to be expected.

She previously said: ‘These treatments can look like tablets or medicines that are injected. It depends on the type of cancer and they are given continuously or intermittently.

‘They can of course also affect the normal cells in your body, which can sometimes cause side effects.

“Hopefully she can handle that and then the chemotherapy will do what it’s supposed to do, and then it’ll be over and hopefully she’ll be fine.”

The preventive treatment Kate carries out, also known as adjuvant chemotherapy, aims to prevent the cancer from returning once the main tumor has been removed from the body.

Cancer can spread to other parts of the body, a process called metastasis, in which small cancer cells break off the main tumor and take root elsewhere.

These “new” cancers can be difficult to detect, so doctors who specialize in treating cancer, called oncologists, often advise patients to undergo preventive chemotherapy in an attempt to eliminate any remaining traces of the disease.

The Princess of Wales with her children in her Mother's Day portrait, which has now taken on significance given her diagnosis

The Princess of Wales with her children in her Mother’s Day portrait, which has now taken on significance given her diagnosis

In a video message released on Friday, Kate said her medical team had advised her to undergo a preventive course of chemotherapy

In a video message released on Friday, Kate said her medical team had advised her to undergo a preventive course of chemotherapy

Preventive chemotherapy is usually administered as an infusion or tablets, where they are then carried throughout the body by the bloodstream.

Depending on the type, chemotherapy can be administered in a hospital or at the patient’s home.

There are more than 100 types of chemotherapy drugs, but they all work in a similar way and circulate through the blood.

The drugs are cytotoxic, meaning they are toxic to cells and especially to cells that are dividing rapidly.

Because cancer cells divide more than healthy cells, they are more affected by chemotherapy, which is why it is used as a treatment for the disease.

However, other types of fast-growing cells, such as hair, bone marrow, skin and the lining of the digestive system, are also damaged.

This leads to some of the famous side effects of chemotherapy, such as hair loss or thinning, fatigue, easier bruising and bleeding, an increased risk of infection, diarrhea or constipation, nausea or vomiting, rash, and more.

Often a patient undergoing chemotherapy is also taking other medications intended to alleviate or combat some of these symptoms.

The specific dosage and type of chemotherapy used varies depending on the type of cancer.

The effectiveness of preventive chemotherapy varies considerably from patient to patient.

Factors that influence its success include the specific type of cancer, when the cancer was originally treated, the patient’s age, and whether he or she has any other health problems.

The specific type of cancer Kate has has not been revealed.

Although only one in ten cases of cancer occur in people under the age of 50, experts are warning of an ‘epidemic’ of the disease among young people.

According to Cancer Research UK, more than 375,000 cases of cancer are discovered in the UK every year, the equivalent of 1,000 every day.

UK figures suggest the 25 to 49 age group contributes to around a tenth (9 percent) of new cases, with almost twice as many women as men in some age groups.

More than a third (36 percent) of new cancer cases occur on average in people aged 75 and older.

Adults aged 50 to 75, meanwhile, account for more than half (54 percent) of all new cases.

Cancers of the breast, prostate, lung and colon make up the vast majority of new diagnoses, accounting for about half in total.

Dr. Shivan Sivakumar, an oncologist at the University of Birmingham, said: ‘There is currently an epidemic of young people getting cancer – under 50s.

‘The cause of this is unknown.’

Professor Andrew Beggs, a colorectal surgeon at the University of Birmingham, said: ‘Cancer that develops at a young age is by no means rare.

‘I run a clinic for early-stage cancer in adults and we are seeing more and more people in their 40s with cancer.’

Professor Lawrence Young, an expert in molecular oncology at the University of Warwick, added: ‘Cancer survival is generally higher in younger people.

‘Early diagnosis and better treatments result in better outcomes, with survival rates doubling over the past 50 years.’

Figures show that approximately one in two people will develop a form of cancer during their lifetime.

Kate’s battle with cancer in her own words: Full emotional video statement from the Princess of Wales

Kate Middletons preventative chemo explained How cancer fighting drugs with brutal

I wanted to take this opportunity to personally thank you for all the wonderful messages of support and for your understanding while I was recovering from surgery.

It’s been an incredibly tough few months for our whole family, but I’ve had a fantastic medical team who have taken great care of me, for which I am so grateful.

In January I had major abdominal surgery in London and at the time my condition was deemed to be non-cancerous. The operation was successful. However, tests after the surgery revealed that cancer was present. My medical team therefore recommended that I undergo a course of preventative chemotherapy and I am now in the early stages of that treatment.

This obviously came as a huge shock, and William and I have done everything we can to process and manage this privately for the sake of our young family.

As you can imagine, this has taken time. It took me time to recover from major surgery before I could start my treatment. But the most important thing is that it took us time to explain everything

George, Charlotte and Louis in a way that suits them, and to reassure them that I will be fine.

As I told them; I am doing well and getting stronger every day by focusing on the things that will help me heal; in my mind, body and spirit.

It is also a great source of comfort and reassurance to have William by my side. As does the love, support and kindness shown by so many of you. It means so much to both of us.

We hope you understand that we as a family now need some time, space and privacy while I complete my treatment. My work has always brought me a deep sense of joy and I look forward to being back when I am able, but for now I must focus on making a full recovery.

At this time I also think of all those whose lives have been touched by cancer. To anyone facing this disease in any form, please do not lose faith and hope. You are not alone.