Milperra crash: Three children seriously injured after horror smash between and an SUV and a sedan

Seven people, including three children, have been taken to hospital after a horror crash in Sydney's south-west.

A sedan and an SUV collided on Milperra Road, Milperra, just after 2am on Saturday, trapping four people.

The three children, aged 10, 14 and 15, and a woman in her 40s were pulled from the SUV by Fire Rescue NSW and raced to hospitals in Westmead with serious injuries.

Three children aged 10, 14 and 15 and a woman in her forties were seriously injured in the accident. Image: 7NEWS

The driver of the sedan, an 18-year-old man, was taken to Liverpool hospital for mandatory tests.

His two passengers, both 18-year-old men, were taken to Liverpool hospital with minor injuries.

Police have cordoned off a crime scene and are investigating.

Three 18-year-olds were taken to hospital, two with minor injuries. Image: 7 NEWS

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