Melbourne man is charged with sexually assaulting 33 women at a Prahran nightclub on Chapel Street

A man will appear in court accused of sexually assaulting 33 women at a Melbourne nightclub.

Victoria Police announced on Tuesday they had charged the 33-year-old man from Cranbourne in the city's south-east with a further 65 counts of sexual assault, after he was previously charged with six of the same offenses on October 27.

The man allegedly sexually assaulted 33 women at a nightclub on Chapel Street in Prahran over three nights: September 23, October 41 and October 21 this year.

He was originally bailed to appear in the Melbourne Magistrates Court on January 11, but has since been summonsed to appear on December 22 on the new charge.

Chapel Street is a popular entertainment district in Melbourne.

A man will appear in the Melbourne Magistrates Court (above) charged with sexually assaulting 33 women at a Prahran nightclub