Tom Curry is one of seven players to retain their place in the starting XV despite a week of controversy
Marcus Smith returns at wing-back after missing out for South Africa, while Freddie Steward moves to the wing.
Henry Arundell returns to the starting line-up for the first time after scoring five tries against Chile in the group stages.
Ben Youngs will fill in at scrum-half, while Alex Mitchell is left out of the team, in what will be his 127th and final cap for England. Jason Leonard is second with 114, while Owen Farrell and Dan Cole both have 111 and 106 respectively.
Following them, Courtney Lawes, with 105 caps, is absent from the squad tonight after announcing his retirement.
Tom Curry moves to blindside flanker, while Oli Chessum replaces George Martin in the second row.
Ben Earl will move to number 8, with Sam Underhill as open side flanker.
Steve Borthwick has also changed his front row, with Ellis Genge, Theo Dan and Will Stuart replacing Joe Marler, Jamie George and Dan Cole.
England: 15 Smith; 14 Steward, 13 Marchant, 12 Tuilagi, 11 Arundell; 10 Farrell (captain), 9 Youngs; 1 Genge, 2 Dan, 3 Stuart, 4 Itoje, 5 Chessum, 6 Curry, 7 Underhill, 8 Earl.
Replacements: George, Rodd, Cole, Ribbans, Ludlam, Care, Ford, Lawrence.