Charlie Sheen’s ex Brooke Mueller is being quizzed by cops over Matthew Perry’s ketamine death as investigators say ‘multiple people’ may be charged

Charlie Sheen’s ex-wife Brooke Mueller has been interviewed “several times” by the LAPD in connection with Matthew Perry’s death after the pair reportedly bonded during a stint in rehab, according to a new report.

Mueller was never arrested or handcuffed in connection with the investigations, sources said In contact that she cooperated in the criminal investigation.

“She has hired attorneys and has had multiple encounters with law enforcement since they arrived at her sober living home with a search warrant. She remains tight-lipped about the situation,” a source told the magazine.

This development follows a separate report that stated investigators could charge “several people” in connection with the actor’s death. DailyMail.com has reached out to Mueller for comment on this story.

‘It’s difficult to say or know exactly what her role is [in Matthew’s death]but she is convinced that she had nothing to do with it.’

Mueller, 46, has had several substance abuse issues over the years. In July 2011, she underwent a drug rehabilitation program. Two years later, her children were removed from her home due to suspected drug use. Mueller then went back to rehab.

Her last public rehab stint took place in August 2019. Between 2008 and 2011, Mueller was married to actor Charlie Sheen. The couple has two sons together, Bob and Max. Their divorce came amid allegations of domestic violence on Sheen’s part.

Perry’s death in October 2023 at the age of 54 shocked the world. The beloved Friends star was found unresponsive in his hot tub at his Los Angeles home. An autopsy attributed his death to the “acute effects of ketamine.”

The amount of ketamine in his blood was in the range used for general anesthesia during surgery. It was listed as the primary cause of death, which was ruled an accident with no foul play suspected, the report said.

People close to the actor told coroner’s investigators that he was undergoing IV ketamine therapy. The decades-old surgical drug has seen a dramatic increase in use in recent years as a treatment for depression, anxiety and pain.

According to the InTouch report, investigators in the case seized a laptop and iPhone belonging to Mueller.

An insider confirmed to InTouch that Mueller and Perry met during rehab. “They formed an unexpected friendship,” the friend said.

Perry said in 2022 that he had spent an estimated $9 million battling his addictions during 15 rehab stays.

In a report by People published Tuesday, a law enforcement investigative source said the investigation is now “nearing completion.”

The source did not clarify who the “multiple people” who may be charged are, adding that any future action will ultimately be determined by the U.S. Attorney’s Office.

However, in December last year, a medical expert speculated that the actor had ‘probably’ obtained ketamine illegally for ‘recreational use’.

Although Perry was undergoing ketamine treatment for anxiety and depression at the time of his death, his autopsy report noted that “the ketamine in his system at death could not have come from that IV therapy.”

Working with the DEA and the US Postal Inspector, LAPD then began investigating the source of the ketamine that “ultimately played a role” in the actor’s death.

At the time, TMZ reported that an ongoing investigation aimed to determine where the actor – who has battled alcoholism and drug addiction for years – had obtained the ketamine.

“Law enforcement sources tell us there is an ongoing investigation into where Matthew obtained the ketamine, which ultimately played a role in his death — and the key questions are who supplied the drug, and under what circumstances,” the outlet reported.

Sources also told the newspaper that “both local police and the DEA have been investigating this case for months, but it is unclear where exactly investigators are in the investigation.”

It was also revealed that they had already spoken to “some important people in Hollywood” who were known to have a history of drug use or abuse. They “could have information that could lead to the source,” the report said.

A year before his death, he opened up about his struggles with addiction and described his journey to sobriety in his memoir Friends, Lovers, and the Big Terrible Thing.

In the tell-all released in 2022, he claimed he was finally sober after multiple failed attempts to get clean and had personally cost him $9 million.

Sources later told DailyMail.com that the ‘reclusive’ younger star allegedly linked up with dating app Raya to deliver drugs to his home, even while under the care of a 24/7 nursing team.

Despite having a nursing team at his $6 million Pacific Palisades home and a live-in, sober companion, Perry managed to have informal contacts who smuggled illegal drugs into him without detection, sources explained in December 2023.

“He met girls on dating apps and had them come over,” insiders claimed.

‘There was a whole bunch of 21 to 25 year olds that he would meet on Raya. They would bring drugs. It was mostly Oxycontin [a powerful opioid pain killer]. He would also get illegal drugs from old girlfriends, there was some kind of network,” said a source.

The source added: ‘I think along [his memoir]Matthew thought it would help him reach the place he described.

“He wrote about what he hoped the situation would be as if it were already there. He wrote the script he wanted.”