Two killed and a DOZEN people injured in devastating five car pile-up on the Great Western Highway near Lithgow, NSW

Two people were killed and a dozen injured in a devastating five-car crash on the western side of the NSW Blue Mountains.

Emergency services are currently on the scene of a serious multi-vehicle crash in the state's Central Tablelands.

The five-vehicle crash occurred along the Great Western Highway, Wallerawang, about 15km north of Lithgow in NSW, with emergency services responding at around 12.50pm on Friday.

Police have cordoned off a crime scene and are awaiting the arrival of specialized police.

Motorists are urged to avoid the area as the Great Western Highway is closed in both directions.

The five-vehicle crash occurred along the Great Western Highway, Wallerawang, about 15km north of Lithgow in NSW, with emergency services responding at around 12.50pm on Friday.

Motorists are urged to avoid the area as the Great Western Highway is closed in both directions

Motorists are urged to avoid the area as the Great Western Highway is closed in both directions

The area is expected to remain a crime scene for some time to come.

β€œIt is shocking news and everyone sends their condolences to the families and loved ones involved in this serious accident,” Bathurst MP Paul Toole said. ABC news.

'It has a far-reaching effect in our local communities.

β€œI know the police have not identified those involved in the incident, but we know it will cause a lot of grief and loss.”

No further information is available at this stage.